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所在位置:所有产品 > 抗体抗原 > 一抗 > STAT5B抗体
STAT5B抗体图片
产品货号:
Z27421
中文名称:
STAT5B抗体
英文名称:
Anti-STAT5B Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-STAT5B Antibody
指标别名STAT5;STAT5B
克隆性Polyclonal
检验物种human,mouse,rat
应用范围WB,FCM
基因名称STAT5B
抗体来源Rabbit
抗体类型IgG
免疫原A synthetic peptide corresponding to a sequence at the C-terminus of human STAT5b (675-703aa KDEVYSKYYTPVPCESATAKAVDGYVKPQ),different from the related mouse and rat sequences by two amino acids.
实际分子量90~95KD
成分500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol.
纯化方式Immunogen affinity purified.
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料STAT5B (Signal transducer and activator of transcription 5B) is a protein that in humans is encoded by the STAT5B gene.STAT5B orthologs have been identified in most placentals for which complete genome data are available.By FISH,Lin et al.(1996) mapped STAT5B to 17q11.2.The protein encoded by this gene is a member of the STAT family of transcription factors.In response to cytokines and growth factors,STAT family members are phosphorylated by the receptor associated kinases,and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein mediates the signal transduction triggered by various cell ligands,such as IL2,IL4,CSF1,and different growth hormones.It has been shown to be involved in diverse biological processes,such as TCR signaling,apoptosis,adult mammary gland development,and sexual dimorphism of liver gene expression.This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APML).The dysregulation of the signaling pathways mediated by this protein may be the cause of the APML.
Uniprot IDP51692
推荐配套试剂Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。
基因名全称signal transducer and activator of transcription 5B
蛋白名全称Signal transducer and activator of transcription 5B
推荐稀释比
Western blot(WB) 1:500~2000
Flow cytometry (FCM) 1~3μg/1×106 cells

相关搜索:STAT5B抗体STAT5B多抗Anti-STAT5B Antibody
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